Bacterial infection imaging with [18F]fluoropropyl-trimethoprim
نویسندگان
چکیده
منابع مشابه
Bacterial endocarditis over prosthetic valves treated with trimethoprim-sulphamethoxazole combination.
During the past few years a number of reports have indicated the therapeutic effectiveness of the new synthetic chemotherapeutic agent trimethoprim (2,4-diamino-5-(3,4,5-trimethoxybenzyl) pyrimidine) used in combination with sulphamethoxazole in a wide range of bacterial infections (Noall, Sewards, and Waterworth, i962; Schneider et al., i965; Akinkugbe et al., I968; Hughes, I969). Staphylococc...
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BACKGROUND Trimethoprim-sulfamethoxazole (TMP-SMZ) has been used extensively for the prevention of Pneumocystis carinii (also referred to as "Pneumocystis jiroveci") pneumonia (PCP) and other opportunistic infections in human immunodeficiency virus (HIV)-infected children. Because the efficacy of TMP-SMZ for treatment of bacterial infections is limited, it is sometimes poorly tolerated, and the...
متن کاملTrimethoprim sulphamethoxazole in neonatal Flavobacterium meningosepticum infection.
During an outbreak of Flavobacterium meningosepticum septicaemia in a neonatal intensive care unit 9 infants were treated with intravenous trimethoprim sulphamethoxazole. Bacteriological cure was achieved in 8 patients; one infant died of massive intraventricular haemorrhage on the first day of treatment. Apart from prolonged persistence of pre-existing thrombocytopenia there was no evidence of...
متن کاملSingle dose trimethoprim for urinary tract infection.
A randomised clinical trial of single dose trimethoprim against a seven day course of co-trimoxazole (trimethoprim/sulphamethoxazole) for the treatment of uncomplicated urinary tract infection was carried out in 106 children aged between 2 and 16 years. Of the 50 children with confirmed urinary tract infections who were followed up 48 hours after treatment with a single dose of trimethoprim all...
متن کاملClinical Diagnosis of Bacterial Infection via FDG-PET Imaging
The key challenge in the treatment of bacterial infection is rapid identification of bacteremia at an early stage of the diseases. Currently available imaging systems such as computed tomography (CT) and magnetic resonance imaging (MRI) can only detect bacterial infection after they have become systemic or have caused significant anatomical tissue damage, and at this stage infection are challen...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2017
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1703109114